An external control arm refers to the use of real-world data (RWD) to describe the progression of disease in a population that is not treated with the experimental drug candidate. External control arms can be used in single-arm clinical trials, in which all enrolled patients receive active treatment, often because a control arm is either infeasible or unethical.

Download this overview to learn how Datavant powers external control arms and why they are important, using an oncology case study as an example.

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