Research

The National COVID Cohort Collaborative (N3C) is an open science effort led by the NIH National Center for Advancing Translational Sciences aimed at accelerating COVID-19 research

Political affiliation has emerged as a potential risk factor for COVID-19, amid evidence that Republican-leaning counties have had higher COVID-19 death rates than Democrat- leaning counties and evidence of a link between political party affiliation and vaccination views.

To learn from the evolving lessons of addressing the COVID-19 pandemic and to bolster the future use of real-world data (RWD) and real-world evidence (RWE), The FDA Foundation, in collaboration with the International Society for Pharmacoepidemiology (ISPE), created The COVID-19 Real-World Evidence Primer.

Elmer V Bernstam, Reuben Joseph Applegate, Alvin Yu, Deepa Chaudhari, Tian Liu, Alex Coda, Jonah Leshin

Objective: Our objective was to evaluate tokens commonly used by clinical research consortia to aggregate clinical data across institutions.

Wataru Ando, Takeshi Horii, Takayuki Uematsu, Hideaki Hanaki, Koichiro Atsuda & Katsuya Otori

The impact of overlapping risk factors on coronavirus disease (COVID-19) severity is unclear. To evaluate the impact of type 2 diabetes (T2D) and obesity on COVID-19 severity, we conducted a cohort study with 28,095 anonymized COVID-19 patients using data from the COVID-19 Research Database from January 1, 2020 to November 30, 2020.

Jacob Wallace, PhD; Anthony Lollo, PhD; Chima D. Ndumele, PhD

In the US, COVID-19 is responsible for hundreds of thousands of excess deaths,1 which has led to considerable interest in strategies to mitigate its impact.

Jane M. Zhu, Renae Myers, K. John McConnell, Ximena Levander, and Sunny C. Lin

The COVID-19 pandemic disrupted mental health services delivery across the US, but the extent and implications of these disruptions are unclear.

Amivantamab is an epidermal growth factor receptor (EGFR)-MET bispecific antibody with immune cell-directing activity.