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Validity of Cardiovascular Data From Electronic Sources

Faraz S. Ahmad, Cheeling Chan, Marc B. Rosenman, Wendy S. Post, Daniel G. Fort, Philip Greenland, Kiang J. Liu, Abel N. Kho, and Norrina B. Allen
The authors sought to understand the degree of agreement of electronic data research networks as compared to data collected by standardized research approaches in a cohort study. The comparisons were made by linking data from MESA (Multi-Ethnic Study of Atherosclerosis), a community-based cohort, with EHR’s from six Chicago-area hospitals. Ultimately, nearly 70 percent had data in both systems and demonstrated mixed results. For some measurements, such as BMI, the correlations between the MESA and EHR data were quite high. For others, such as systolic blood pressure, the correlation coefficient was only 0.39.

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Payment Reform Needed to Address Health Disparities of Undiagnosed Diabetic Retinopathy in the City of Chicago

Dustin D. French, Jess J. Behrens, Kathryn L. Jackson, Abel N. Kho, Theresa L. Walunas, Charlesnika T. Evans, Michael Mbagwu, Curtis E. Margo, and Paul J. Bryar
By linking together medical encounter data from a number of different Chicago hospital systems, the authors identified 150,661 patients with diabetes (out of a total of two million patients). Using that information, the study estimated the geographic distribution of undiagnosed diabetic retinopathy and found that low-income and minority areas had a disproportionate rate of undiagnosed diabetic retinopathy. Based on that, a new screening mechanism that is not currently funded by Medicare or Medicaid was suggested.

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Does Spatial Access to Primary Care Affect Emergency Department Utilization for Nonemergent Conditions?

Jamie Fishman, Sara McLafferty, and William Galanter
The study attempted to understand the utilization of emergency departments for preventable conditions at the individual and neighborhood level by linking together emergency department admissions from four Chicago hospitals. By combining the data, the authors showed that individuals in medically underserved areas (MUAs) had a larger chance of emergency department use that could have been prevented.

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Distance from Hospital Impacts Adverse Event Detection After Outpatient Endoscopy

Kathryn L. Jackson, Satyender Goel, Abel N. Kho, and Rajesh N. Keswani
Using the HealthLNK Data Repository, the authors sought to understand the relationship between hospital utilization and distance from the index hospital for patients with adverse events following an ambulatory endoscopy. Using mortality as the endpoint, the authors found that of the 86 patients (of the 22,898 in the study) who had early mortality, nearly half did not return to the index hospital. In total, there was a statistically significant relationship between a patient’s utilization of their index hospital and their proximity.

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An Evaluation of Recurrent Diabetic Ketoacidosis, Fragmentation of Care, and Mortality Across Chicago, Illinois

James A. Mays, Kathryn L. Jackson, Teresa A. Derby, Jess J. Behrens, Satyender Goel, Mark E. Molitch, Abel N. Kho, and Amisha Wallia
Some patients with diabetes are hospitalized repeatedly for diabetic ketoacidosis (DKA), which is typically associated with worse clinical outcomes. The authors analyzed recurrent DKA and fragmentation of care across six institutions in the Chicago area, using Datavant technology to understand when the same patient would have different DKA episodes in different hospitals. The study found that of the 3,615 patients, 21.6% had recurrent DKA; of the 780 recurrent patients, 125 were hospitalized at more than one hospital.

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Design and Implementation of a Privacy Preserving Electronic Health Record Linkage Tool in Chicago

Abel N. Kho, John P. Cashy, Kathryn L. Jackson, Adam R. Pah, Satyender Goel, Jörn Boehnke, John Eric Humphries, Scott Duke Kominers, Bala N. Hota, Shannon A. Sims, Bradley A. Malin, Dustin D. French, Theresa L. Walunas, David O. Meltzer, Erin O. Kaleba, Roderick C. Jones, and William L. Galanter
The study discusses the design and implementation of a tool that created a secure, privacy-preserving linkage of electronic health record (EHR) data across multiple sites in Chicago. There are a number of uses for this technology, including in clinical research and understanding the fragmentation of care. The software documented in the study was able to link data across the six institutions, resulting in five million unique patient records while de-duplicating seven million records. Today, the software is part of the Datavant offering.

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