Datavant supports transparent research that utilizes real-world data in a privacy preserving manner. Below, we highlight research efforts that have used Datavant technology to link real-world data for the benefit of patients and the public good.
The VA does not capture health encounters that occur outside its facilities. Therefore, any analyses of health-care utilization will miss certain data; this is particularly important for at-risk populations, where understanding utilization will enable better and less fragmented care. VA data was linked with Chicago’s HealthLNK Data Repository to find that of the 13,948 veterans who were homeless or at risk of becoming homeless, 17 percent of those veterans received some or all of their care in the community.
The Patient-Centered Outcomes Research Network (PCORnet) connects health systems, health plans, EHR data, and claims data to facilitate real-world clinical research. Datavant powers the linking of PCORnet. In this study, the authors looked to identify and understand the extent to which a clinical data research network and a health plan network contained consistent data on the patient level. Of the 549 patients from the EHR record who had claims with the health plan, sixty percent had consistent antibiotic exposure while 43.1% had a matched claims record.
Most patients with cirrhosis have low Model for End-Stage Liver Disease-Sodium (MELD-Na) scores. The ability for the MELD-Na score to predict patient outcomes at low scores remains unclear. The researchers were able to link data from across Chicago to understand what patients might be eligible; from there, 7922 patients were identified, with 3999 patients having low MELD-Na scores. Further analyses were performed to show that, though patients with high MELD-Na scores had higher rates of mortality and were more likely to die of liver-related causes, even patients with low MELD-Na scores had high rates of liver-related mortality.
This study examined a retrospective cohort as part of the ADAPTABLE trial (Aspirin Dosing: A Patient-centric Trial Assessing Benefits and Long-Term Effectiveness). The trial was designed to compare the efficacy of different doses of Aspirin for the prevention of atherosclerotic cardiovascular disease events. By linking claims data from Anthem with data from the Patient-Centered Outcomes Research Network (PCORnet), the investigators were able to follow participants and understand their health outcomes without direct follow-up or bringing them into a trial site.